LABORATORY

Pharm. Chemistry Lab-I (Organic Medicinal Chemistry Lab)-

 

This Lab is Utilized for the Synthesis and identification of Organic Medicinal Compounds. The Lab is equipped with modern infrastructure like distillation still, rotary vacuum evaporator, hot air ovens and fume cupboard. For the synthesis of medicinal compounds a reterosynthetic strategy is planned in a manner so that the theoretical as well as practical yield of the compound or the intermediate is maximum. The medicinal compounds may be synthesized in single step or more than five steps. Thermo labile compounds are treated at low temperatures using rotary vacuum evaporators. Fume cupboard is used for the explosive (like metal hydrides) synthetic reactions or when the reagents are corrosive or lachrymatory in nature. After the synthesis of medicinal compounds its purity is checked by Thin layer chromatography and melting point determination techniques. The compound is tested for its identification and limit tests as per standards.

Pharm. Chemistry Lab-II (Inorganic Medicinal Chemistry Lab)-

 

This lab is Utilized for the synthesis and identification of inorganic medicinal compounds. The Lab is equipped with modern infrastructure like distillation still, hot air ovens and fume cupboard. Generally inorganic medicinal compounds are synthesized in 2 or three steps very easily. Fume cupboard is used for the explosive (like metal hydrides) synthetic reactions or when the reagents are corrosive or lachrymatory in nature. After the synthesis of inorganic medicinal compounds its purity is checked by assay procedures described in pharmacopoeia of India. Then compound is tested for its identification and limit tests as per the Pharmacopoeia of India. The impurity contents should be within acceptable limits. The inorganic compounds should be free from heavy metals impurities which are highly toxic to human body.

Pharmaceutical Analysis Lab: -

 

This Lab is utilized for the Pharmaceutical Analysis of organic, inorganic compounds of synthetic or natural origin. Various Assay procedures are adopted for the analysis. This lab is equipped with glasswares for pharmaceutical analysis like burette, pipette, volumetric flasks, measuring cylinders etc.The analysis lab is associated with a balance room harboring 30 highly sensitive chemical balances for the preparation of volumetric reagents. The lab is also associated with a instrumentation room having modern and sophisticated instruments like UV-Visible spectrophotometer, Flame photometer, Ph Meter, Potentiometer etc. The Lab is also provided with the Preparation room for the preparation of volumetric reagents

Instrumentation room: -

 

This lab is having modern and sophisticated instruments like UV-Visible spectrophotometer, Flame photometer, Ph Meter, Potentiometer, Karl Fischer apparatus, colorimeter etc. This Lab is utilized for the instrumental methods of analysis of medicinal compounds and biological samples. UV-Visible spectrophotometer is a sensitive instrument for estimations of very minute quantities (micrograms and Pico grams) of medicinal compounds and also Organic Medicinal Compounds can be estimated simultaneously in multidrug dosage forms by this instrument. Flame Photometer is used to determine sodium and potassium contents of the inorganic and organic medicinal compounds. Biochemical analysis of biological samples like blood, urine, sputum and stool can be done by colorimeter or UV-Visible Spectrophotometer. Potentiometer is used for the potentiometric titrations. Karl Fischer apparatus is used for the determination of moisture in organic or inorganic samples.

Pharmaceutics Lab-I (General Pharmacy Lab)-

 

This laboratory provides elementary knowledge about the manufacturing of pharmaceutical preparations. This lab is also utilized to teach about the dispensing of the drugs in a hospital by a pharmacist and about community pharmacy practice. The lab is used for the preparation of aromatic waters, syrups, liniments, lozenges, lotions, tinctures, poultice etc.

Pharmaceutics Lab-II (Unit Operations Lab)-

 

This laboratory imparts knowledge of pharmaceutical engineering and fluid mechanics. various pharmaceutical operations such as drying, distillation, crystallization, size reduction processes, mixing, filtration etc utilized in pharmaceuticals manufacturing process are studied in detail in this lab. The lab is also associated with the machine room equipped with several advanced machinery performing operations of pharmaceutical purposes. The lab is also equipped with engineering drawing instruments and the drawing boards for the purpose of designing the equipments used for industrial processes.

Pharmaceutics Lab-III (Pharm. Technology Lab)-

 

This laboratory is Utilized to prepare different dosage forms solid, liquid & semi solids. The laboratory is equipped with Orifice meter, venturimeter, Reynold’s apparatus, ointment slab, dissolution appararus, disintegration apparatus, tablet hardnesstester, friability test apparatus, bulk density apparatus etc. These equipments are used to prepare dosage forms and then to evaluate the various properties of the dosage forms like flow parameters of liquid dosage forms and the hardness and disintegration properties of tablets. The laboratory is also utilized for for the preparation and evaluation of cosmetics. The laboratory is also utilized for teaching pharmacokinetics of the Drug in the human body.

Machine Room (Industrial Lab)-

 

The machine room is associated with Pharmaceutics Lab-II and III. This room harbors heavy machines to be operated for the preparation and evaluation of the drug dosage forms. The machines available are hand operated single punch tablet machine for the preparation of tablets, ampoule filling and sealing machine, ampoule washing machine, capsule filling machine, ball mill for the breaking and grinding of hard marterials, tablet coating machine for the preparation of enteric coated tablets, ointment tube filling and crimping machine, autoclave for sterilization of the glasswares and chemicals and hot air oven for dryng of the granules. This room is very much useful for providing pharmaceutical industry basrd knowledge of different types of machines used in pharma industries.

Pharm. Biotechnology Lab (Microbiology and Biochemistry Lab)-

 

This lab is used for the study of microbiological and biochemical processes of bacterial, mammalian cells. This lab is also utilized for plant tissue culture. This lab is associated with a aseptic chamber in which bacterial cell can be transferred and cultured aseptically. This lab is utilized for performing the microbiological assay of antibiotics and vitamins. The lab consists of autoclave, BOD incubator, Refrigerator, Laminar air Flow Unit, Bacterial Colony Counter, Centrifuge machine,  etc. Autoclave is used for making the sterile chemicals and glassware to be used in bacterial or plant tissue culture. The Lab has facility to study the enzymatic reactions and to perform the biochemical analysis of blood, Urine etc. The Laminar Air flow Unit provides a aseptic area in the aseptic chamber used for the aseptic transfer of bacterial cultures. The BOD incubator maintains a steady temperature of 37 degree suitable for the growth of bacterial cells on the culture media. The lab is also utilized to study the antibacterial activity of organic medicinal compounds.

Human Anatomy and Physiology Lab:-

 

This lab is well maintained with charts and models of Human Organs and Organ
 Systems like Respiratory, Digestive, excretory, reproductive, circulatory, lymphatic, skeleton systems. Various human bones with complete human skeleton is available for the study of complete anatomy and physiology of the humans in healthy condition. The lab also consists of Microscopes and instruments for studying the blood and haemopoitic system. The lab is used for haematological studies of human blood. The lab also consist of equipments like stethoscope, sphygmomamometer and respirometer. Stethoscope is used to diagnose the abnormal heart and pulserate. Sphygmomanometer is used to determine actual blood pressure of human body. Respirometer is used to study the capacity of Lungs. The lab is also having various permanent microscopic slides of human cells, tissues and organs.

Pharmacology Lab:-

 

This Laboratory is utilized to determine the action of drugs on the animal or its isolated tissues. The lab is well equipped with types of specialized equipments like Convulsiometer for testing anticonvulsant effect of drugs on rats and mice, Eddy’s Hot Plate for testing analgesic effect, Plethysmograph, rota rod apparatus and cooks pole climbing apparatus for testing antipsychotic effect, Single and double unit Organ bath with recording drums are utilized for experiments  on isolated tissues from the animals. The experimental animals used are albino, rats, mice, rabbit and Guinea  Pigs. The animals are kept with ease in an animal house associated with the Lab. The lab is also utilized for determination of acute and chronic toxicities of the new drug molecules.

Pharmacognosy Lab with museum:-

 

This Lab consists of 150 organized as well as unorganized crude drugs. The lab provides esteemed guidelines to the students regarding natural source of drugs and phytochemical screening through various instruments like binocular microscope, TLC apparatus, Clevenger apparatus, soxhlet extractor. The laboratory is utilized for morphological and anatomy study of drugs of natural origin. The laboratory has equipments for the extraction, fractionation, isolation and characterization of the organic drug molecules from medicinal plants. The lab is associated with a museum in which herbal drugs are displayed. A herbarium is also maintained in the lab for identification of the medicinal plants. A medicinal plant garden in the campus is available to catter the need of pharmacognosy lab. The medicinal plants are tagged with their biological nomenclature and categories used in chemotaxonomy.

Animal House:-

 

Animal house is associated with Pharmacology Lab. Animal house is utilized for keeping the experimental animals with ease. They are provided with healthy food and water. Animal house harbors several experimental animals like albino rats and mice, rabbits and guinea pigs. Animal house is registered with CPCSEA (Committee for the purpose of control and supervision of experiments on animals). Animal house has sufficient facilities for the breeding and feed storage area. Separate cage cleaning area and quarantine for rabbits is also available. Institutional Animal Ethics committee is made in the institution which is looking after the welfare of the experimental animals.

Computer Lab: -

 

Computer Lab is equipped with 40 PCs with multimedia facility and internet connection. The Lab is used to teach the application of the different computer softwares for the purpose of storing and utilizing the data for pharmacy practice. The computer lab is also used for study of Quantitative structure activity relationship of drug molecules. Different softwares like Chemdraw and chemDBsoftlite are available for facilitating the computer aided drug molecule designing and assessment of their chemical and physical constants. The lab also assists in understanding the molecular basis of the diseases and drugs used in their treatment by the Bioinformatics and Cheminformatics.